PROTEINSCAPE

To overcome the growing complexity of proteomics experiments, Brukers bioinformatics platform, ProteinScape™, collects all your data and arranges it in a way that reflects the way you work. Customizable tables and viewers present the information such that the advanced data mining features help you get the maximum out of your data. Sophisticated reports help you efficiently communicate your findings. ProteinScape is the key to running successful proteomics projects. Proteomics Data Handling Made Easy: ProteinScape viewers enable fast and interactive evaluation and validation of proteomics data. Real-time updating of the linked displays speeds browsing and information management. TECHNICAL DETAILS: - (Client/Server based architecture): • ProteinScape Server with a central server and five or more clients • ProteinScape Workstation, with the whole system installed on a single PC. - (Protein quantitation): • Labelfree quantitation • Various isobaric and non-isobaric labels, e.g. SILAC • Alternatively augmented by 3rd party packages Skyline and MaxQuant. - (Report Templates): • Peptides and proteins: search parameters, ID results, quantitation results • Glycans and glycopeptides: search parameters, ID results • Publication-ready report generation. - (Database management): • User management with read/write access administration • Project-oriented data management Database structure reflecting laboratory workflow, including separation protocols, free text notes etc. - (Advanced result processing): • Export in different formats for seamless knowledge transfer • Simple and comparative queries for data mining. - (Glycan Analysis): • Pre-search spectra classification • GlycoQuest glycan search engine • Linked result tables • Glycan-related viewers • Dedicated glycan queries and reports. - (Protein database search features): • ProteinExtractor - compilation of protein lists from different origins • Decoy validation • Automatic triggering of searches • Second-round searches • Support of different fragmentation types, e.g. CID, ETD, ECD, etc. • Automatic result assessment . - (Interactive viewers): • Gel viewer • LC-MS survey viewer • Spectrum viewer • Protein sequence viewer • 3D protein structure viewer • Glycan structure viewer • Quantitation statistics viewer • Venn diagram viewer • Chromatography Viewer • Sequence Editor • Histogram Viewer. - (Supported mass spectrometers): • All Bruker MS systems • Thermo MS systems via dta, mgf • Waters MS systems via pkl, mgf • ABI MS systems via mgf.