AMAZON™ SPEED

AmaZon speed: Redefining Ion Trap performance for small molecule Applications. The amaZon speed ion trap sets a new analytical standard for small molecule and screening applications. Fundamental improvements to the well proven amaZon platform offer dramatically enhanced speed, and mass resolution. MS/MS efficiency and reproducible quantitation, are delivering unsurpassed performance levels. With a 10x higher MS/MS sensitivity over current platforms, Zero Delay Alternating™ switching at a minimum of 20 Hz MS acquisition rate, this ion trap meets the increasing demand of  the pharmaceutical, chemical and clinical market. amaZon builds upon Bruker’s vast experience in ion trap technology, and is designed specifically to enhance capabilities in research areas such as  proteomics, metabolomics, compound screening and identification, and detailed chemical analysis. TECHNICAL DETAILS: Unmatched ion trap performance through innovation: • Greatly increased MS/MS duty cycle for more productive data acquisition • Highest ion trap mass accuracy through proprietary RF generator design • Leading dual ion funnel technology for unparalleled sensitivity • Zero Delay Alternating™ for polarity switching with a minimum of 20 Hz MS acquisition speed • New SMART isolation and fragmentation • Unrivalled scan speed of 52,000 u/sec at a peak width < 0.5 u for resolution of doubly charged ions • Support of fastest UPLC applications at a maximum duty cycle. APPLICATIONS: • MSn for Structure Analysis: The identification of drug metabolites and their structure verification are a vital part in pharma discovery and development. Software features like the FragmentExplorerTM are the ideal tools for structure confirmation taking advantage of the fast and sensitive stepwise MSn fragmentation of the amaZon speed ion trap. Bruker‘s MetaboliteToolsTM software suite provides confident metabolite prediction as well as detection and interpretation of new compounds. • Drug quantitation: Reliable and routine quantification is a task so far reserved for triple quadrupole instruments. The enhanced speed and reproducibility of the amaZon speed in MRM experiments enables the reliable quantification of target compounds in diverse matrices. • Walk up Compass OpenAccess workflows: The intuitive and workflow-oriented GUI of the Compass OpenAccess software supports the flexibility and speed of the amaZon speed as an ideal solution for multi-user industrial, clinical or teaching labs. The web-based client server system is ideally suited for workflows like  e.g. quality control (QC), recombinant protein MW verification or automatic library searches.